KT 5720; KT 5720. Catalog No. B9002. Add to Compare. Email. protein kinase A inhibitor, potent and selective. Skip to the end of the images gallery.
av A Miemois · Citerat av 3 — http://www.oph.fi/txtpageLast.asp?path=1,438,5720,19918. Utbildningsstyrelsen. 2004. Grunderna för läroplanen för den grundläggande utbildningen 2004.
Cited in 27 publications. It blocks PKA signaling through competitive inhibition of ATP with a K i value of 60 nM. 1 Reported IC 50 values vary widely depending upon ATP concentration tested and can range from 56 nM (low ATP) to 3 µM (physiologic ATP). 2,3 Non-specific effects of KT 5720 include inhibition of phosphorylase kinase, PDK1, MEK, MSK1, PKBα, and GSK3β at concentrations as effective as or more potent than MW 537.61, Purity > 98%. Potent, selective protein kinase A (Ki = 60 nM) inhibitor. Reversibly arrests human skin fibroblasts in the G1 phase. Cell permeable.
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Grunderna för läroplanen för den grundläggande utbildningen 2004. or 5720 KILE. Label. -.
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NE571ND-C9716PIN, PHI, 1250. NE571NSA571N, PHIL, 900. NE572, 10.
KT-5720 (but not its close derivatives, K252a and K252b) reversed multidrug resistance of LM1/MDR cell line at non-toxic concentrations and increased accumulation of rhodamine 123 (Rh123).
KT 5720 reversibly arrests human skin fibroblasts in the G1 phase. KT 5720 is an inhibitor of PKA. KT5720 attenuates hyperpolarization-activated cyclic nucleotide-gated (HCN) channel currents, decreasing amplitude and increasing action potential threshold. This inhibition results in decreases in intracellular Ca2+ levels and suppression of dorsal root ganglion (DRG) neuron excitability. Buy KT 5720 - an affordable, high quality PKA inhibitor from Hello Bio, a trusted supplier for life science researchers worldwide KT-5720 has numerous actions unrelated to its ability to inhibit PKA. This suggests that other PKA inhibitors should be used in its place. Although KT 5720 has been extremely useful in examining the roles of PKA in cell signaling, it may now be time for them to be superseded by other methods. KT-5720 has numerous actions unrelated to its ability to inhibit PKA. This suggests that other PKA inhibitors should be used in its place.
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Catalogue Number: 420320: Brand Family: Calbiochem® Synonyms: PKA Inhibitor VII KT 5720 is a potent, selective inhibitor of protein kinase A (Ki = 60 nM). KT 5720 reversibly arrests human skin fibroblasts in the G1 phase. KT 5720 is an inhibitor of PKA. KT5720 attenuates hyperpolarization-activated cyclic nucleotide-gated (HCN) channel currents, decreasing amplitude and increasing action potential threshold. This inhibition results in decreases in intracellular Ca2+ levels and suppression of dorsal root ganglion (DRG) neuron excitability.
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(1). Datasheet / COA / SDS. Protein Kinase A Inhibitors Small Molecule. Catalog #. Availability.
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KT 5720 | C32H31N3O5 | CID 3844 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities,
Målning ut- och invändigt. 2,600: — i1.1--1 2. ,-firo,r,r,,A. J.KT -5.31..,[j, .1 .ks,k4sweat. KT. Beställ MEAT & DORIA 26356 Elhiss strömställare CITROËN Berlingo / Berlingo First (MF, GJK. (Skicka recension).
386, 23, 192, 206, 1, 15, 146, 51, 5,720, 198, 143, 79, 126, 235, 288, 39, 96, 14, 106, 1, 8, 5,044, 417, 51, 34, 13, 295, 121, 27, 12, 41, 49, 32, 30, 2, 498, 1,051
Skip to the end of the images gallery. Skip to the beginning of the images gallery. Grouped product items; Size Price Stock Qty; 50ug: $96.00. Ship with 5-10 days : 100ug: $182.00. Ship with 5-10 days : 250ug: $431.00. Ship with 5-10 days : Wolfgang R. Dostmann, Christian K. Nickl, in Handbook of Cell Signaling (Second Edition), 2010 ATP Binding Site-Targeted Inhibitors. Synthetic protein kinase inhibitors that are competitive with ATP and specific for PKA and/or PKG represent a structurally diverse group of small ligand compounds [24, 47].Polycyclic aromatics, such as isoquinolinesulfonyl and napthalenesulfonyl compounds (“H ChEBI Name KT 5720: ChEBI ID CHEBI:85085: Definition An organic heterooctacyclic compound that is 1H,1'H-2,2'-biindole in which the nitrogens have undergone formal oxidative coupling to positions 2 and 5 of hexyl (3S)-3-hydroxy-2-methyltetrahydrofuran-3-carboxylate (the 2R,3S,5S product), and in which the 3 and 3' positions of the biindole moiety have also undergone formal oxidative coupling 2019-06-05 KT-5720 (108068-98-0) is a potent selective protein kinase A inhibitor: PKA (K i = 60 nM).
Add to Compare. Email. protein kinase A inhibitor, potent and selective. Skip to the end of the images gallery. Registration enables users to use special features of this website, such as past order histories, retained contact details for faster checkout, review submissions, and special promotions. KT-5720 58HV29I28S Overview Structure Names 3: Identifiers 3: Active Moiety 1: Notes 1: Audit Info References 9: Moieties 1: Substance Class Select categories you would like to watch.